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  4. PGLYRP4 Antibody, FITC conjugated

PGLYRP4 Antibody, FITC conjugated

  • 中文名稱：
    PGLYRP4兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA017865LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PGLYRP4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PGLYRP4
  • 別名：
    Peptidoglycan recognition protein 4 antibody; Peptidoglycan recognition protein I-beta antibody; Peptidoglycan recognition protein intermediate beta antibody; Pglyrp4 antibody; PGLYRPIbeta antibody; PGRP-I-beta antibody; PGRP4_HUMAN antibody; PGRPIB antibody; SBBI67 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Peptidoglycan recognition protein 4 protein (18-317AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
  • 基因功能參考文獻(xiàn)：
    1. a significant induction of three PGLYRPs 2-4 in primary human corneal epithelial cells (HCECs) exposed to live or heat-killed Candida albicans, is reported. PMID: 26039076
    2. This study demonistrated that PGLYRP4 single-nucleotide polymorphisms is risk of Parkinson's disease. PMID: 24838182
    3. Results describe the function of mammalian antimicrobial peptidoglycan recognition proteins 3 and 4, and show that they are a new class of bactericidal and bacteriostatic proteins. PMID: 16354652
    4. Data are consistent with previous reports of association of psoriasis with genes on 1q21, and suggest a role for Pglyrp4 in skin biology. PMID: 16362825
  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    N-acetylmuramoyl-L-alanine amidase 2 family
  • 組織特異性：
    Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongu
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30015

    OMIM: 608198

    KEGG: hsa:57115

    STRING: 9606.ENSP00000352672

    UniGene: Hs.58356