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PHKG2 Antibody

  • 中文名稱：
    PHKG2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA017928ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: PHKG2 antibody at 3.4µg/ml + HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 47, 44 kDa
      Observed band size: 47 kDa
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA017928ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA017928ESR2HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PHKG2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    PHKG2Phosphorylase b kinase gamma catalytic chain antibody; liver/testis isoform antibody; PHK-gamma-LT antibody; PHK-gamma-T antibody; EC 2.7.11.19 antibody; PSK-C3 antibody; Phosphorylase kinase subunit gamma-2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Phosphorylase b kinase gamma catalytic chain, liver/testis isoform protein (237-406AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM.
  • 基因功能參考文獻(xiàn)：
    1. These cases add to the current knowledge of clinical variability in patients with PHKG2 mutations. Long term studies, involving follow-up of these patients into adulthood, are needed PMID: 24389071
    2. Patients with PHKG2 mutations have a severe hepatic phenotype within the heterogeneous GSD IX disorder. A defect in PHKG2 should be considered in patients with suspected glycogenosis associated with significant liver fibrosis and cirrhosis. PMID: 24326380
    3. PHKG2 mutations are associated with Glycogen storage disease type IX PMID: 17689125
  • 相關(guān)疾?。?/div>
    Glycogen storage disease 9C (GSD9C)
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 8931

    OMIM: 172471

    KEGG: hsa:5261

    STRING: 9606.ENSP00000455607

    UniGene: Hs.65735