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PIGM Antibody

  • 中文名稱：
    PIGM兔多克隆抗體
  • 貨號：
    CSB-PA017976GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    PIGM
  • 別名：
    PIGM antibody; GPI mannosyltransferase 1 antibody; EC 2.4.1.- antibody; GPI mannosyltransferase I antibody; GPI-MT-I antibody; Phosphatidylinositol-glycan biosynthesis class M protein antibody; PIG-M antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human PIGM
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
  • 基因功能參考文獻(xiàn)：
    1. B cells but not red cells are glycosylphosphatidylinositol deficient in PIGM-associated inherited glycosylphosphatidylinositol deficiency, caused by a core promoter mutation that abrogates Sp1 binding. PMID: 25293775
    2. Studies indicate that mutations in PGM1 by exome sequencing cause hypoglycemia and liver abnormalities. PMID: 23329837
    3. Mutation substantially reduces transcription of PIGM and blocks mannosylation of glycosylphosphatidylinositol(GPI), leading to partial but severe deficiency of GPI. PMID: 16767100
  • 相關(guān)疾病：
    Glycosylphosphatidylinositol deficiency (GPID)
  • 亞細(xì)胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    PIGM family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18858

    OMIM: 610273

    KEGG: hsa:93183

    STRING: 9606.ENSP00000357069

    UniGene: Hs.552810