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PIGO Antibody

  • 中文名稱(chēng):
    PIGO兔多克隆抗體
  • 貨號(hào):
    CSB-PA855068LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA855068LA01HU at dilution of 1:100
    • Immunofluorescent analysis of A549 cells using CSB-PA855068LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng):
    Rabbit anti-Homo sapiens (Human) PIGO Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    PIGO antibody; UNQ632/PRO1249 antibody; GPI ethanolamine phosphate transferase 3 antibody; EC 2.-.-.- antibody; Phosphatidylinositol-glycan biosynthesis class O protein antibody; PIG-O antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human GPI ethanolamine phosphate transferase 3 protein (219-420AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated

    本頁(yè)面中的產(chǎn)品,PIGO Antibody (CSB-PA855068LA01HU),的標(biāo)記方式是Non-conjugated。對(duì)于PIGO Antibody,我們還提供其他標(biāo)記。見(jiàn)下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱(chēng) 應(yīng)用
    HRP CSB-PA855068LB01HU PIGO Antibody, HRP conjugated ELISA
    FITC CSB-PA855068LC01HU PIGO Antibody, FITC conjugated
    Biotin CSB-PA855068LD01HU PIGO Antibody, Biotin conjugated ELISA
  • 克隆類(lèi)型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond.
  • 基因功能參考文獻(xiàn):
    1. PIGO deficiency shows variable phenotypes from infantile lethality to mild learning difficulties PMID: 28337824
    2. Disease associated PIGO missense mutations resulted in decreased activity in vitro. PMID: 28327575
    3. Novel PIGO mutations expand the clinical spectrum of PIGO abnormalities to include epileptic encephalopathy with mild elevation of alkaline phosphatase (ALP). PMID: 24417746
    4. Our data identify PIGO as the second gene associated with HPMRS and suggest that a deficiency in GPI-anchor synthesis is the underlying molecular pathomechanism of HPMRS. PMID: 22683086
  • 相關(guān)疾病:
    Hyperphosphatasia with mental retardation syndrome 2 (HPMRS2)
  • 亞細(xì)胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族:
    PIGG/PIGN/PIGO family, PIGO subfamily
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 23215

    OMIM: 614730

    KEGG: hsa:84720

    STRING: 9606.ENSP00000339382

    UniGene: Hs.522099