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  4. PIK3IP1 Antibody, Biotin conjugated

PIK3IP1 Antibody, Biotin conjugated

  • 中文名稱：
    PIK3IP1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA850293LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PIK3IP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PIK3IP1
  • 別名：
    HGFL antibody; hHGFL(S) antibody; Kringle domain containing protein HGFL antibody; Kringle domain-containing protein HGFL antibody; MGC17330 antibody; P3IP1_HUMAN antibody; Phosphoinositide 3 kinase interacting protein 1 antibody; Phosphoinositide-3-kinase-interacting protein 1 antibody; PIK3IP1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Phosphoinositide-3-kinase-interacting protein 1 protein (22-168AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Negative regulator of hepatic phosphatidylinositol 3-kinase (PI3K) activity.
  • 基因功能參考文獻：
    1. Findings indicate that colon cancer associated transcript 1 (non-protein coding) (CCAT1) was upregulated in osteosarcoma tissues and cells, and was involved in the proliferation and migration of osteosarcoma via regulating miR-148a/phosphatidyl inositol 3-kinase interacting protein 1 (PIK3IP1) signal pathway. PMID: 28549102
    2. These results suggest that the novel PI3K regulator PIK3IP1 plays an inhibitory role in T-cell activation. PMID: 22706993
    3. PIK3IP1-v1 is a novel splicing isoform of PIK3IP1. Both of them are located on cell membrane and can induce cell apoptosis. PMID: 19088825
    4. PIK3IP1 directly binds to the p110 catalytic subunit and down modulates PI3K activity. Suggested that PIK3IP1 is a new type of PI3K regulator. PMID: 17475214
    5. PIK3IP1 is an important regulator of PI3K in vivo, and its dysregulation can contribute to liver carcinogenesis PMID: 18632611

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  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24942

    KEGG: hsa:113791

    STRING: 9606.ENSP00000215912

    UniGene: Hs.26670