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PLCH1 Antibody

  • 中文名稱(chēng)：
    PLCH1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA018136GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    PLCH1
  • 別名：
    1-phosphatidylinositol 4 antibody; 1-phosphatidylinositol-4 antibody; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1 antibody; 5-bisphosphate phosphodiesterase eta-1 antibody; DKFZp434C1372 antibody; KIAA1069 antibody; MGC117152 antibody; Phosphoinositide phospholipase C-eta-1 antibody; Phospholipase C-eta-1 antibody; Phospholipase C-like protein 3 antibody; PLC-eta-1 antibody; PLC-L3 antibody; PLCeta1 antibody; Plch1 antibody; PLCH1_HUMAN antibody; PLCL3 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human PLCH1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes.
  • 基因功能參考文獻(xiàn)：
    1. High fertilization (56.06%) and pregnancy (41.7%) rates accomplished in this study following ICSI-AOA indicated that expression profiles of PLCzeta, PAWP, and TR-KIT were low in globozoospermic individuals PMID: 27089467
    2. A molecular model of the PLCeta2 EF-hand domain, constructed based upon the structure of calmodulin, suggested both EF-loops may participate in Ca(2+) -binding. PMID: 24123053
    3. The PLCH1 rs181696 single-nucleotide polymorphism was strongly associated with an increased risk of squamous cell carcinoma. PMID: 22658813
    4. molecular cloning of PLC-eta1 and PLC-eta2 PMID: 15583837
    5. The identification of a novel PLC isoform in the brains of human and mouse, named PLC-eta, which contains the conserved pleckstrin homology domain, X and Y domains for catalytic activity and the C2 domain. PMID: 15702972

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  • 亞細(xì)胞定位：
    Cytoplasm. Membrane.
  • 組織特異性：
    Expressed in brain and to a lower extent in lung. In brain, it is found in cerebrum, cerebellum and spinal cord.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 29185

    OMIM: 612835

    KEGG: hsa:23007

    STRING: 9606.ENSP00000345988

    UniGene: Hs.567423