PLEK2 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q9NYT0
基因名：

PLEK2
別名：

Pleckstrin 2 (mouse) homolog antibody; Pleckstrin 2 antibody; Pleckstrin-2 antibody; PLEK 2 antibody; PLEK2 antibody; PLEK2_HUMAN antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human PLEK2
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation.
基因功能參考文獻(xiàn)：
1. expression of PLEK2, the strongest gene to classify melanoma patients, in CD45(-) subsets illustrates the importance of analyzing whole blood cells for biomarker studies PMID: 21698244
2. Pleckstrin 2 was cloned; its mRNA is widely expressed in a variety of cell lines. PMID: 15865208
3. pleckstrin-2 uses its modular domains to bind to membrane-associated phosphatidylinositols generated by PI3K, whereby it coordinates with the actin cytoskeleton in lymphocyte spreading and immune synapse formation. PMID: 17008542
4. These results suggest that PLEK2 is involved in actin rearrangement in a PI 3-kinase dependent manner. PMID: 17658464
亞細(xì)胞定位：

Cell projection, lamellipodium membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 19238

OMIM: 608007

KEGG: hsa:26499

STRING: 9606.ENSP00000216446

UniGene: Hs.170473