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  4. PLK5 Antibody

PLK5 Antibody

  • 中文名稱：
    PLK5兔多克隆抗體
  • 貨號：
    CSB-PA175015
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from COLO cells, Jurkat cells and HeLa cells, using PLK5 antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PLK5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PLK5
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from internal of Human PLK5.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.
  • 基因功能參考文獻：
    1. we report a three-nucleotide deletion near the C-region of Plk5 that is specifically associated with the lymphatic metastasis in patients with clear cell renal cell carcinoma PMID: 26908440
    2. The human polo-like kinase 5 gene is significantly silenced in astrocytoma and glioblastoma multiforme by promoter hypermethylation, suggesting a tumor suppressor function for this gene. PMID: 21245385
  • 亞細胞定位：
    Nucleus, nucleolus. Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily
  • 組織特異性：
    Expressed in the brain, neurons and glial cells. Also expressed in highly differentiated cells, such as the serous acini in the parotid gland, distal and proximal tubules of the kidney, tubules of the seminal gland, Kupffer cells and some hepatocytes in t
  • 數(shù)據(jù)庫鏈接：

    HGNC: 27001

    KEGG: hsa:126520

    STRING: 9606.ENSP00000466248

    UniGene: Hs.195352