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POC5 Antibody

  • 中文名稱：
    POC5兔多克隆抗體
  • 貨號(hào)：
    CSB-PA843309LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA843309LA01HU diluted at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) POC5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    POC5
  • 別名：
    C5orf37 antibody; Centrosomal protein POC5 antibody; FLJ35779 antibody; hPOC5 antibody; MGC120442 antibody; MGC120443 antibody; MGC120444 antibody; OTTHUMP00000222116 antibody; OTTHUMP00000222453 antibody; Poc5 antibody; POC5 centriolar protein antibody; POC5 centriolar protein homolog (Chlamydomonas) antibody; POC5 centriolar protein homolog antibody; POC5_HUMAN antibody; Protein of centriole 5 antibody; Proteome of centriole 5 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Centrosomal protein POC5 protein (373-485AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，POC5 Antibody (CSB-PA843309LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于POC5 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA843309LB01HU POC5 Antibody, HRP conjugated ELISA
    FITC CSB-PA843309LC01HU POC5 Antibody, FITC conjugated
    Biotin CSB-PA843309LD01HU POC5 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Essential for the assembly of the distal half of centrioles, required for centriole elongation.
  • 基因功能參考文獻(xiàn)：
    1. Common variant rs6892146 of POC5 is associated with the development of adolescent idiopathic scoliosis in the Chinese population. PMID: 29189569
    2. Depletion of CEP295 blocks the incorporation of POC5 and POC1B into the distal portion of centrioles and suppresses the post-translational modification of centriolar microtubules . Our study thus uncovers a new role for CEP295 during centriole elongation. PMID: 27185865
    3. Mutations in the POC5 gene contribute to the occurrence of idiopathic scoliosis. PMID: 25642776
    4. Data indicate that overexpression of the centrin interactor POC5 leads to the assembly of linear, centrin-dependent structures. PMID: 23844208
    5. hPOC5, a conserved centrin-binding protein that contains Sfi1p-like repeats is characterized. PMID: 19349582

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  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localized to the distal portion of centrioles.
  • 蛋白家族：
    POC5 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 26658

    OMIM: 617880

    KEGG: hsa:134359

    STRING: 9606.ENSP00000410216

    UniGene: Hs.432726