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POU3F1 Antibody

  • 中文名稱：
    POU3F1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA018396LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Rat stomach tissue, Mouse stomach tissue
      All lanes: POU3F1 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 46 kDa
      Observed band size: 46 kDa
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA018396LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) POU3F1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    POU3F1
  • 別名：
    class 3 antibody; Oct-6 antibody; OCT6 antibody; Octamer-binding protein 6 antibody; Octamer-binding transcription factor 6 antibody; OTF-6 antibody; OTF6 antibody; PO3F1_HUMAN antibody; POU class 3 homeobox 1 antibody; POU domain antibody; POU domain class 3 transcription factor 1 antibody; POU domain transcription factor SCIP antibody; pou3f1 antibody; SCIP antibody; transcription factor 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human POU domain, class 3, transcription factor 1 protein (59-257AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，POU3F1 Antibody (CSB-PA018396LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于POU3F1 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA018396LB01HU POU3F1 Antibody, HRP conjugated ELISA
    FITC CSB-PA018396LC01HU POU3F1 Antibody, FITC conjugated
    Biotin CSB-PA018396LD01HU POU3F1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters. Acts as a transcriptional repressor of myelin-specific genes.
  • 基因功能參考文獻(xiàn)：
    1. Combined high OATP1A2/high OCT6 may be a potential predictor of response to anthracycline/taxane-based chemotherapy in breast cancer PMID: 24671357
    2. CpG island hypermethylation contributes to down-regulation of Oct-6 mRNA expression in hepatocellular carcinoma. PMID: 21448695
    3. Our results suggest that Tst-1 and Skn-1a regulate expression of MMPs in keratinocytes and effect both the expression and activation of these proteolytic enzymes. PMID: 17195013
    4. Strict control of Pou3f1 transgene expression is critical to proper myelination, and factors responsible for Pouf31 downregulation during myelination may play important roles in the development of peripheral neuropathies. PMID: 17959798
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    POU transcription factor family, Class-3 subfamily
  • 組織特異性：
    Expressed in embryonal stem cells and in the developing brain.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 9214

    OMIM: 602479

    KEGG: hsa:5453

    STRING: 9606.ENSP00000362103

    UniGene: Hs.1837