PPCS Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q9HAB8
基因名：

PPCS
別名：

COAB antibody; FLJ11838 antibody; MGC117357 antibody; MGC138220 antibody; OTTHUMP00000008433 antibody; Phosphopantothenate--cysteine ligase antibody; Phosphopantothenoylcysteine synthetase antibody; PPC synthetase antibody; Ppcs antibody; PPCS_HUMAN antibody; RP11-163G10.1 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human PPCS
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the second step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. Has a preference for ATP over CTP as a cosubstrate.
基因功能參考文獻：
1. Exome sequencing in five individuals from two unrelated families presenting with dilated cardiomyopathy revealed biallelic mutations in PPCS. PMID: 29754768
2. Oxygen transfer studies found that 18O from [carboxyl-18O] phosphopantothenate is incorporated into AMP or CMP produced during PPCS catalysis, consistent with the formation of a phosphopantothenoyl cytidylate or phosphopantothenoyl adenylate intermediate PMID: 19683078
蛋白家族：

PPC synthetase family
數(shù)據(jù)庫鏈接：

HGNC: 25686

OMIM: 609853

KEGG: hsa:79717

STRING: 9606.ENSP00000361642

UniGene: Hs.706662