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  4. PPFIBP2 Antibody, Biotin conjugated

PPFIBP2 Antibody, Biotin conjugated

  • 中文名稱：
    PPFIBP2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA847688LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PPFIBP2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PPFIBP2
  • 別名：
    PPFIBP2 antibody; Liprin-beta-2 antibody; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2 antibody; PTPRF-interacting protein-binding protein 2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Liprin-beta-2 protein (101-400AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
  • 基因功能參考文獻(xiàn)：
    1. Analysis of the role of liprin-beta1 and liprin-beta2 has shown that while liprin-beta1 contributes positively to tumour cell motility in vitro; liprin-beta2 has a negative effect on both cell motility and invasion. PMID: 26663347
    2. rs12791447 is associated with prostate cancer susceptibility in Asians. mRNA levels of PPFIBP2 are differentially expressed in prostate tumours and paired normal tissues. PMID: 26443449
    3. Knockdown of either Rab17 or liprin-beta2 restores invasiveness of ERK2-depleted cells, indicating that ERK2 drives invasion of MDA-MB-231 cells by suppressing expression of these genes. PMID: 22328529
    4. analysis of crystal structure of the central coiled-coil domain from human liprin-beta2 PMID: 21462929
  • 蛋白家族：
    Liprin family, Liprin-beta subfamily
  • 組織特異性：
    Widely expressed.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9250

    OMIM: 603142

    KEGG: hsa:8495

    STRING: 9606.ENSP00000299492

    UniGene: Hs.655714