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  4. PPP1R9A Antibody

PPP1R9A Antibody

  • 中文名稱：
    PPP1R9A兔多克隆抗體
  • 貨號：
    CSB-PA018557GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    PPP1R9A
  • 別名：
    FLJ20068 antibody; KIAA1222 antibody; NEB1_HUMAN antibody; Neurabin I antibody; Neurabin-1 antibody; Neurabin-I antibody; Neurabin1 antibody; NeurabinI antibody; Neural tissue specific F actin binding protein I antibody; Neural tissue-specific F-actin-binding protein I antibody; NRB 1 antibody; NRB I antibody; NRB1 antibody; NRBI antibody; Ppp1r9a antibody; Protein phosphatase 1 regulatory (inhibitor) subunit 9A antibody; Protein phosphatase 1 regulatory subunit 9A antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human PPP1R9A
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity.
  • 基因功能參考文獻：
    1. MARCKS and PPP1R9A might contribute to spine loss in schizophrenia and bipolar disorder through their interactions. PMID: 25757715
    2. CHN2, ABCB1 and PPP1R9A expression on chromosome 7 is implicated in the pathogenesis of hepatosplenic T-cell lymphoma distinguishing it from other malignancies. PMID: 25057852
    3. Studies suggest that any change in substrate specificity of the spinophilin : PP1 holoenzyme complex was probably due to direct modification of a PP1 substrate binding surface. PMID: 22284538
    4. PPP1R9A gene is imprinted, with preferential expression from the maternal allele in embryonic skeletal muscle and extra-embryonic tissues, but biallelic expression in other embryonic tissues. PMID: 15286155
  • 亞細胞定位：
    Cytoplasm, cytoskeleton. Cell junction, synapse, synaptosome.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 14946

    OMIM: 602468

    KEGG: hsa:55607

    STRING: 9606.ENSP00000405514

    UniGene: Hs.21816