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  4. PPP2CB Antibody

PPP2CB Antibody

  • 中文名稱：
    PPP2CB兔多克隆抗體
  • 貨號：
    CSB-PA00985A0Rb
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Antibody at 2μg/ml + EC109 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/15000 dilution
      Predicted band size: 34 kDa
      Observed band size: 34 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA00985A0Rb at dilution of 1:50
    • Immunofluorescent analysis of Hela cells using CSB-PA00985A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • IHC image of CSB-PA00985A0Rb diluted at 1:260 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA00985A0Rb diluted at 1:260 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA00985A0Rb at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PPP2CB Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    PP2A beta antibody; PP2A-beta antibody; PP2AB_HUMAN antibody; PP2Abeta antibody; PP2CB antibody; Ppp2cb antibody; Protein phosphatase 2 (formerly 2A); catalytic subunit; beta isoform antibody; Protein phosphatase 2 catalytic subunit beta isozyme antibody; Protein phosphatase 2; catalytic subunit; beta isoform antibody; Protein phosphatase 2A catalytic subunit beta isoform antibody; Protein phosphatase type 2A catalytic subunit antibody; Serine/threonine protein phosphatase 2A catalytic subunit beta antibody; Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform protein (1-309AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，PPP2CB Antibody (CSB-PA00985A0Rb)，的標記方式是Non-conjugated。對于PPP2CB Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA00985B0Rb PPP2CB Antibody, HRP conjugated ELISA
    FITC CSB-PA00985C0Rb PPP2CB Antibody, FITC conjugated
    Biotin CSB-PA00985D0Rb PPP2CB Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
  • 基因功能參考文獻：
    1. The GAS41-PP2Cbeta complex dephosphorylates p53 at serine 366 and regulates its stability PMID: 21317290
    2. Claspin may be one of the phosphoproteins through which PP2A(Aalpha/Cbeta) affects Chk1 phosphorylation when ATR is activated by human immunodeficiency virus-1 Vpr. PMID: 17210576
    3. These data strongly support a recent proposal that a segment at 8p21.3 contains crucial prostate cancer tumor suppressors. PMID: 18460741
  • 亞細胞定位：
    Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole. Note=In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.
  • 蛋白家族：
    PPP phosphatase family, PP-1 subfamily
  • 數據庫鏈接：

    HGNC: 9300

    OMIM: 176916

    KEGG: hsa:5516

    STRING: 9606.ENSP00000221138

    UniGene: Hs.491440