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PRDM12 Antibody

  • 中文名稱:
    PRDM12兔多克隆抗體
  • 貨號(hào):
    CSB-PA003849
  • 規(guī)格:
    ¥1090
  • 圖片:
    • Western Blot analysis of A549 cells using PRDM12 Polyclonal Antibody
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    PRDM12
  • 別名:
    PRDM12 antibody; PFM9PR domain zinc finger protein 12 antibody; EC 2.1.1.- antibody; PR domain-containing protein 12 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human PRDM12.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    WB, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Involved in the positive regulation of histone H3-K9 dimethylation.
  • 基因功能參考文獻(xiàn):
    1. The natural history of the PRDM12-CIP disorder. PMID: 26975306
    2. PRDM12 and its functional fly homolog Hamlet are evolutionary conserved master regulators of sensory neuronal specification and play a critical role in pain perception PMID: 25891934
    3. Prdm12 is a key factor in the orchestration of sensory neurogenesis. PMID: 26005867
    4. Down-regulation of PRDM12 is associated with the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion PMID: 14523459
  • 相關(guān)疾病:
    Neuropathy, hereditary sensory and autonomic, 8 (HSAN8)
  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    Class V-like SAM-binding methyltransferase superfamily
  • 組織特異性:
    Not found in adult tissues except in dorsal root ganglia.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 13997

    OMIM: 616458

    KEGG: hsa:59335

    UniGene: Hs.495311