PRTFDC1 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q9NRG1
基因名：

PRTFDC1
別名：

FLJ11888 antibody; HHGP antibody; OTTHUMP00000019332 antibody; Phosphoribosyl transferase domain containing 1 antibody; phosphoribosyltransferase domain containing protein 1 antibody; Phosphoribosyltransferase domain-containing protein 1 antibody; PRDC1_HUMAN antibody; prtfdc1 antibody; Uncharacterized protein PRTFDC1 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Human PRTFDC1
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage.
基因功能參考文獻(xiàn)：
1. We found evidence for PRTFDC1 as a potential novel PTSD gene, a finding that awaits further replication. PMID: 25456346
2. These results demonstrate that PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse. PMID: 21818316
3. The PRTFDC1 structure has been determined at 1.7 A resolution with bound GMP. The overall structure and GMP binding mode are very similar to that observed for HPRT. PMID: 21054786
4. epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PMID: 17599052
蛋白家族：

Purine/pyrimidine phosphoribosyltransferase family
數(shù)據(jù)庫(kù)鏈接：

HGNC: 23333

OMIM: 610751

KEGG: hsa:56952

STRING: 9606.ENSP00000318602

UniGene: Hs.405619