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PSMA5 Antibody, FITC conjugated

  • 中文名稱：
    PSMA5兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA018870LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PSMA5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PSMA5
  • 別名：
    Macropain zeta chain antibody; Multicatalytic endopeptidase complex zeta chain antibody; Proteasome (prosome macropain) subunit alpha type 5 antibody; Proteasome alpha5 subunit antibody; Proteasome component 5 antibody; Proteasome subunit alpha type 5 antibody; Proteasome subunit alpha type-5 antibody; Proteasome subunit zeta antibody; Proteasome zeta chain antibody; PSA5_HUMAN antibody; PSC5 antibody; PSMA5 antibody; ZETA antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Proteasome subunit alpha type-5 protein (124-180AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
  • 基因功能參考文獻(xiàn)：
    1. Selective upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome zeta chain and isopeptidase T in fetal Down syndrome. PMID: 11771738
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Peptidase T1A family
  • 組織特異性：
    Expressed in fetal brain (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 9534

    OMIM: 176844

    KEGG: hsa:5686

    STRING: 9606.ENSP00000271308

    UniGene: Hs.485246