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Pdk3 Antibody

  • 中文名稱：
    Pdk3兔多克隆抗體
  • 貨號：
    CSB-PA852852LA01MO
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Rat liver tissue
      All lanes: Pdk3 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 48 kDa
      Observed band size: 48 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Mus musculus (Mouse) Pdk3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    Pdk3
  • 別名：
    Pdk3 antibody; [Pyruvate dehydrogenase antibody; acetyl-transferring)] kinase isozyme 3 antibody; mitochondrial antibody; EC 2.7.11.2 antibody; Pyruvate dehydrogenase kinase isoform 3 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Mouse, Human, Rat
  • 免疫原：
    Recombinant Mouse [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial protein (131-362AA)
  • 免疫原種屬：
    Mus musculus (Mouse)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，Pdk3 Antibody (CSB-PA852852LA01MO)，的標(biāo)記方式是Non-conjugated。對于Pdk3 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA852852LB01MO Pdk3 Antibody, HRP conjugated ELISA
    FITC CSB-PA852852LC01MO Pdk3 Antibody, FITC conjugated
    Biotin CSB-PA852852LD01MO Pdk3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species.
  • 基因功能參考文獻(xiàn)：
    1. demonstrate that the increased PDK3 activity in patient fibroblasts (PDK3(R158H)) leads to the attenuation of PDC through hyper-phosphorylation of E1 at selected serine residues PMID: 27388934
  • 亞細(xì)胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    PDK/BCKDK protein kinase family
  • 數(shù)據(jù)庫鏈接：