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Pdxp Antibody

  • 中文名稱：
    Pdxp兔多克隆抗體
  • 貨號(hào)：
    CSB-PA017749LA01MO
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Rat brain tissue
      All lanes: Pdxp antibody at 2.8μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 32 kDa
      Observed band size: 32 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Mus musculus (Mouse) Pdxp Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    Pdxp
  • 別名：
    Pdxp antibody; Cin antibody; Plp antibody; Plpp antibody; Pyridoxal phosphate phosphatase antibody; PLP phosphatase antibody; EC 3.1.3.3 antibody; EC 3.1.3.74 antibody; Chronophin antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Mouse, Rat
  • 免疫原：
    Recombinant Mouse Pyridoxal phosphate phosphatase protein (1-292AA)
  • 免疫原種屬：
    Mus musculus (Mouse)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，Pdxp Antibody (CSB-PA017749LA01MO)，的標(biāo)記方式是Non-conjugated。對(duì)于Pdxp Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA017749LB01MO Pdxp Antibody, HRP conjugated ELISA
    FITC CSB-PA017749LC01MO Pdxp Antibody, FITC conjugated
    Biotin CSB-PA017749LD01MO Pdxp Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Functions as a pyridoxal phosphate (PLP) phosphatase, which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), with order of substrate preference PLP > PNP > PMP and therefore plays a role in vitamin B6 metabolism. Also functions as a protein serine phosphatase that specifically dephosphorylates 'Ser-3' in proteins of the actin-depolymerizing factor (ADF)/cofilin family like CFL1 and DSTN. Thereby, regulates cofilin-dependent actin cytoskeleton reorganization, being required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phosphothreonines in LIMK1. Does not dephosphorylate peptides containing phosphotyrosine.
  • 基因功能參考文獻(xiàn)：
    1. Results provided novel evidence that PLPP is involved in controlling dendritic spine as well as synaptic plasticity. It showed also for the first time the role of PLPP in GluN functionality via regulation of GluN2A interaction with postsynaptic proteins. These findings suggest that PLPP/CIN may play an important role in information storage and recall capacity, which manifests as a learning memory. PMID: 27212638
    2. Evolutionary and structural analyses of mammalian haloacid dehalogenase-type phosphatases AUM and chronophin provide insight into the basis of their different substrate specificities. PMID: 24338473
    3. Dimer formation is essential for an intermolecular arginine-arginine-tryptophan stacking interaction that positions a critical histidine residue in the substrate specificity loop of chronophin for PLP coordination. PMID: 24338687
    4. analysis of pyridoxal phosphatase cloning, expression and tissue distribution PMID: 14522954
  • 亞細(xì)胞定位：
    Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    HAD-like hydrolase superfamily
  • 組織特異性：
    Ubiquitous. highly expressed in brain (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接：