Phospho-NIFK (T234) Antibody

產(chǎn)品詳情

Uniprot No.：

Q9BYG3
基因名：

NIFK
別名：

hNIFK antibody; MK67I_HUMAN antibody; MKI67 FHA Domain Interacting Nucleolar Phosphoprotein antibody; MKI67 FHA domain-interacting nucleolar phosphoprotein antibody; mki67ip antibody; NOPP34 antibody; Nucleolar phosphoprotein Nopp34 antibody; Nucleolar protein interacting with the FHA domain of pKI 67 antibody; Nucleolar protein interacting with the FHA domain of pKI-67 antibody; pKi67 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse
免疫原：

Synthesized peptide derived from Human NIFK around the phosphorylation site of T234.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

IHC, IF, ELISA

推薦稀釋比：

Protocols：

Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

基因功能參考文獻(xiàn)：
1. NIFK is required for lung cancer progression via the RUNX1-dependent CK1alpha repression, which activates TCF4/beta-catenin signaling in metastasis and the Ki-67-dependent regulation in cell proliferation. PMID: 26984280
2. The RNA recognition motif of NIFK is required for rRNA maturation during cell cycle progression. PMID: 25826659
3. Potential encounter complexes of the Ki67FHA receptor and hNIFK peptide are misregistered states of the beta-sheet. PMID: 21539773
4. nmr analysis of the solution structure of the FHA domain of human Ki67 and mapping of the binding surface for NIFK binding PMID: 14659764
5. Better basal gene expression was observed by co-cultured respiratory epithelial cells compared to dispase dissociated cells. PMID: 17891046
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亞細(xì)胞定位：

Nucleus, nucleolus. Chromosome. Note=Localizes to mitotic chromosomes in conjunction with MKI67.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 17838

OMIM: 611970

KEGG: hsa:84365

STRING: 9606.ENSP00000285814

UniGene: Hs.367842