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RAB28 Antibody, FITC conjugated

  • 中文名稱：
    RAB28兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA019179LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RAB28 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RAB28
  • 別名：
    RAB28 antibody; Ras-related protein Rab-28 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Ras-related protein Rab-28 protein (98-218AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn)：
    1. In summary, we identified a novel rare "likely pathogenic" variant--RAB28 c.68C>T--in a Korean patient with cone-rod dystrophy. PMID: 28388261
    2. Deleterious mutations in RAB28 result in a classic CRD phenotype and are an infrequent cause of CRD in the Spanish population. PMID: 25356532
    3. Autosomal-recessive cone-rod dystrophy is associated with RAB28 mutations. PMID: 23746546
    4. Crystal structures of Rab28 in the active (GppNHp-bound) and inactive (GDP-3'P-bound) forms at 1.5 and 1.1A resolution were reported. PMID: 19026641
  • 相關(guān)疾病：
    Cone-rod dystrophy 18 (CORD18)
  • 亞細(xì)胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 組織特異性：
    Isoform S is detected in most tissues investigated: cortex, liver, kidney, skeletal muscle, adipose tissue, testis, urothelium, lung, bone marrow and retinal pigment epithelium (RPE). Isoform L 2 is widely and abundantly expressed all tissues. Isoform 3 i
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 9768

    OMIM: 612994

    KEGG: hsa:9364

    STRING: 9606.ENSP00000328551

    UniGene: Hs.656060