RAI14 Antibody, HRP conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RAI14 Polyclonal antibody
Uniprot No.：

Q9P0K7
基因名：

RAI14
別名：

Ankycorbin antibody; Ankyrin repeat and coiled coil structure containing protein antibody; Ankyrin repeat and coiled-coil structure-containing protein antibody; DKFZp564G013 antibody; KIAA1334 antibody; NORPEG antibody; Novel retinal pigment epithelial cell protein antibody; RAI13 antibody; RAI14 antibody; RAI14_HUMAN antibody; Retinoic acid induced 14 antibody; Retinoic acid induced protein 14 antibody; Retinoic acid-induced protein 14 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Ankycorbin protein (242-346AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhesion. May also promote integrity of Sertoli cell tight junctions at the blood-testis barrier.
基因功能參考文獻：
1. TCGA database and Kaplan-Meier Plotter mining results showed that compared to those with RAI14 low mRNA expression levels, Gastric Cancer patients with RAI14 high mRNA expression levels had remarkably lower time of both overall survival and disease-free survival. Cox multivariate survival analyses shows high expression of RAI14 was the only independent predictor of unfavorable prognosis in patients with gastric cancer. PMID: 29654694
2. Subcellular localization of NORPEG in retinal pigment epithelial (ARPE-19) cells varies with cell density, with predominantly nuclear localization in nonconfluent cells, but a cytoplasmic localization in confluent cultures. PMID: 16729964
亞細胞定位：

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cell cortex. Cell junction. Nucleus.
組織特異性：

Highly expressed in placenta, muscle, kidney and testis. Moderately expressed in heart, brain, lung, liver and intestine. Isoform 2 is widely expressed and expressed in fetal and adult testes, and spermatozoa.
數據庫鏈接：

HGNC: 14873

OMIM: 606586

KEGG: hsa:26064

STRING: 9606.ENSP00000427123

UniGene: Hs.431400