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  4. RERE Antibody

RERE Antibody

  • 中文名稱：
    RERE兔多克隆抗體
  • 貨號：
    CSB-PA011436
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA011436(RERE Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA011436(RERE Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    RERE
  • 別名：
    1110033A15Rik antibody; AI414665 antibody; ARG antibody; arginine glutamic acid dipeptide (RE) repeats antibody; arginine glutamic acid dipeptide repeats antibody; Arginine glutamic acid dipeptide repeats protein antibody; Arginine-glutamic acid dipeptide repeats protein antibody; ARGININE-GLUTAMIC ACID REPEATS-ENCODING GENE antibody; ARP antibody; ATN1L antibody; Atr2 antibody; atrophin 1 like antibody; Atrophin 1 like protein antibody; Atrophin 1 related protein antibody; atrophin 2 antibody; atrophin related protein antibody; ATROPHIN-1-ASSOCIATED PROTEIN antibody; Atrophin-1-like protein antibody; Atrophin-1-related protein antibody; atrophin-2 antibody; ATROPHIN-RELATED PROTEIN antibody; AW742570 antibody; DNB1 antibody; FLJ38775 antibody; KIAA0458 antibody; mKIAA0458 antibody; NEDBEH antibody; OTTHUMP00000001701 antibody; Rere antibody; RERE_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human RERE
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.
  • 基因功能參考文獻：
    1. suggest that mutations in RERE cause a genetic syndrome and that haploinsufficiency of RERE might be sufficient to cause many of the phenotypes associated with proximal 1p36 deletions PMID: 27087320
    2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    3. Observational study of gene-disease association. (HuGE Navigator) PMID: 18597038
    4. The mouse ortholog of RERE is required for embryonic development PMID: 14645126
  • 相關(guān)疾病：
    Neurodevelopmental disorder with or without anomalies of the brain, eye, or heart (NEDBEH)
  • 亞細胞定位：
    Nucleus. Note=Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.
  • 組織特異性：
    Widely expressed. Expressed in tumor cell lines.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9965

    OMIM: 605226

    KEGG: hsa:473

    STRING: 9606.ENSP00000338629

    UniGene: Hs.463041