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  4. RGS18 Antibody, FITC conjugated

RGS18 Antibody, FITC conjugated

  • 中文名稱：
    RGS18兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA019649LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RGS18 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RGS18
  • 別名：
    Regulator of G protein signalling 13 antibody; Regulator of G Protein Signalling 18 antibody; Regulator of G-protein signaling 18 antibody; RGS 18 antibody; RGS13 antibody; RGS18 antibody; RGS18_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Regulator of G-protein signaling 18 protein (28-84AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i) alpha-1, G(i) alpha-2, G(i) alpha-3 and G(q) alpha.
  • 基因功能參考文獻(xiàn)：
    1. These findings indicate cross-talk between platelet activation and inhibition pathways at the level of RGS18 and Gq. PMID: 22234696
    2. Data show that that SPL/RGS/SHP1 complexes are present in resting platelets where constitutive phosphorylation of SPL(Y398) creates an atypical binding site for SHP-1. PMID: 22210881
    3. molecular cloning and characterization of RGS18 as a regulator of G protein signalling in human platelets PMID: 11955952
    4. gene mapped to chromosome 1. PMID: 16484797
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 組織特異性：
    Expressed in peripheral leukocytes, bone marrow, platelet, spleen and fetal liver.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 14261

    OMIM: 607192

    KEGG: hsa:64407

    STRING: 9606.ENSP00000356430

    UniGene: Hs.440890