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  4. RNASEH2C Antibody, FITC conjugated

RNASEH2C Antibody, FITC conjugated

  • 中文名稱：
    RNASEH2C兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA837441LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RNASEH2C Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RNASEH2C
  • 別名：
    RNASEH2C antibody; AYP1 antibody; Ribonuclease H2 subunit C antibody; RNase H2 subunit C antibody; Aicardi-Goutieres syndrome 3 protein antibody; AGS3 antibody; RNase H1 small subunit antibody; Ribonuclease HI subunit C antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Ribonuclease H2 subunit C protein (1-164AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
  • 基因功能參考文獻：
    1. This study reviewed that Neurologic Phenotypes Associated with Mutations in RNASEH2C in patients with Aicardi-Goutieres Syndrome. PMID: 27643693
    2. Examination of the effect of several Aicardi-Goutieres Syndrome-related mutations in the C subunit of RNase H2. PMID: 19015152
    3. Describes an RNASEH2C pseudogene that is located close to the SRY gene on chromosome Y. PMID: 8244390
  • 相關(guān)疾?。?/div>
    Aicardi-Goutieres syndrome 3 (AGS3)
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    RNase H2 subunit C family
  • 組織特異性：
    Widely expressed.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24116

    OMIM: 610329

    KEGG: hsa:84153

    STRING: 9606.ENSP00000308193

    UniGene: Hs.718438