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  4. RUFY3 Antibody

RUFY3 Antibody

  • 中文名稱：
    RUFY3兔多克隆抗體
  • 貨號：
    CSB-PA765974LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, 293T whole cell lysate, K562 whole cell lysate, SH-SY5Y whole cell lysate
      All lanes: RUFY3 antibody at 3.71µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 53, 56, 71, 65 kDa
      Observed band size: 53 kDa
    • Immunofluorescence staining of Hela cells with CSB-PA765974LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RUFY3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RUFY3
  • 別名：
    Protein RUFY3 antibody; rap2 interacting protein x antibody; Rap2 interacting protein x isoform 2 antibody; Rap2-interacting protein x antibody; RIPx antibody; Rpipx antibody; Rufy3 antibody; RUFY3_HUMAN antibody; RUN and FYVE domain containing 3 antibody; Singar antibody; Singar1 antibody; Single axon regulated protein antibody; single axon related 1 antibody; Single axon-regulated protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Protein RUFY3 protein (243-352AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，RUFY3 Antibody (CSB-PA765974LA01HU)，的標(biāo)記方式是Non-conjugated。對于RUFY3 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA765974LB01HU RUFY3 Antibody, HRP conjugated ELISA
    FITC CSB-PA765974LC01HU RUFY3 Antibody, FITC conjugated
    Biotin CSB-PA765974LD01HU RUFY3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Plays a role in the generation of neuronal polarity formation and axon growth. Implicated in the formation of a single axon by developing neurons. May inhibit the formation of additional axons by inhibition of PI3K in minor neuronal processes. Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery. Plays a role in cytoskeletal organization by regulating the subcellular localization of FSCN1 and DBN1 at axonal growth cones. Promotes gastric cancer cell migration and invasion in a PAK1-dependent manner.
  • 基因功能參考文獻(xiàn)：
    1. these findings provide important evidence that PAK1 can positively regulate RUFY3 expression, which contribute to the metastatic potential of gastric cancer cells PMID: 25766321
    2. Rab5(Q79L) interacts with the carboxyl terminus of RUFY3 PMID: 20376209
  • 亞細(xì)胞定位：
    Cytoplasm. Endomembrane system. Cell projection, invadopodium. Perikaryon. Cell projection. Cell projection, growth cone. Cell projection, filopodium. Cell projection, lamellipodium.
  • 組織特異性：
    Overexpressed in gastric cancer cells and tissues (at protein level).
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30285

    OMIM: 611194

    KEGG: hsa:22902

    STRING: 9606.ENSP00000370394

    UniGene: Hs.740904