SF3A3 Antibody

說明書

產品詳情

Uniprot No.：

Q12874
基因名：

SF3A3
別名：

SF3A3 antibody; SAP61 antibody; Splicing factor 3A subunit 3 antibody; SF3a60 antibody; Spliceosome-associated protein 61 antibody; SAP 61 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human SF3A3
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes.
基因功能參考文獻：
1. The interaction between CSR1 and SF3A3 led to migration of SF3A3 from nucleus to cytoplasm. The cytoplasmic redistribution of SF3A3 significantly reduced the splicing efficiency of epidermal growth factor receptor and platelet-derived growth factor receptor. PMID: 27148859
亞細胞定位：

Nucleus speckle. Nucleus.
蛋白家族：

SF3A3 family
組織特異性：

Ubiquitous.
數據庫鏈接：

HGNC: 10767

OMIM: 605596

KEGG: hsa:10946

STRING: 9606.ENSP00000362110

UniGene: Hs.77897