SHQ1 Antibody, Biotin conjugated
產(chǎn)品詳情
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產(chǎn)品名稱(chēng)：
Rabbit anti-Homo sapiens (Human) SHQ1 Polyclonal antibody
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Uniprot No.：
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基因名：
SHQ1
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別名：
SHQ1 antibody; Protein SHQ1 homolog antibody
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宿主：
Rabbit
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反應(yīng)種屬：
Human
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免疫原：
Recombinant Human Protein SHQ1 homolog protein (6-223AA)
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免疫原種屬：
Homo sapiens (Human)
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標(biāo)記方式：
Biotin
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克隆類(lèi)型：
Polyclonal
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抗體亞型：
IgG
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純化方式：
>95%, Protein G purified
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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產(chǎn)品提供形式：
Liquid
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應(yīng)用范圍：
ELISA
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Protocols：
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儲(chǔ)存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點(diǎn)詳情
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功能：
Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA.
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基因功能參考文獻(xiàn)：
- Results from a study on gene expression variability markers in early-stage human embryos shows that SHQ1 is a putative expression variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
- The expression of GRIM-1 and GRP78 was negatively correlated in human non-small cell lung cancer (NSCLC) tissues, and the down-regulation of GRP78 by GRIM-1 provides a possible mechanism for their interaction. PMID: 25081541
- these results provide insight into the Shq1/dyskerin (Cbf5) interaction that plays a critical role in H/ACA RNP biogenesis and assembly in eukaryotes PMID: 25553844
- study suggests that GRIM-1 (SHQ1) might act as a co-tumor suppressor in the prostate PMID: 21931644
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亞細(xì)胞定位：
Cytoplasm, cytosol. Nucleus, nucleoplasm. Note=May at least partially shuttle between cytosol and nucleoplasm. In the nucleoplasm, exhibits a granular pattern, but is excluded from nucleoli and Cajal bodies. Absent from most H/ACA-box RNA transcription sites.
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蛋白家族：
SHQ1 family
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數(shù)據(jù)庫(kù)鏈接：
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