搡老女人多毛老妇女中国,日韩亚洲欧美中文高清在线,人妻少妇一区二区三区,色妞色综合久久夜夜,日本熟妇xxxx

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SHROOM3 Antibody

SHROOM3 Antibody

  • 中文名稱：
    SHROOM3兔多克隆抗體
  • 貨號(hào)：
    CSB-PA844740LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA844740LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA844740LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SHROOM3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SHROOM3
  • 別名：
    APXL3 antibody; hShrmL antibody; MSTP013 antibody; Protein Shroom3 antibody; Shrm antibody; Shrm3 antibody; SHRM3_HUMAN antibody; ShrmL antibody; Shroom family member 3 antibody; Shroom-related protein antibody; shroom3 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Protein Shroom3 protein (1309-1571AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，SHROOM3 Antibody (CSB-PA844740LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于SHROOM3 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA844740LB01HU SHROOM3 Antibody, HRP conjugated ELISA
    FITC CSB-PA844740LC01HU SHROOM3 Antibody, FITC conjugated
    Biotin CSB-PA844740LD01HU SHROOM3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays.
  • 基因功能參考文獻(xiàn)：
    1. Two protein-truncating de novo mutations in two independent cases in SHROOM3 strongly implicates this protein in severe human neural tube defects. PMID: 25805808
    2. variants disrupting the actin-binding domain of SHROOM3 may cause podocyte effacement and impairment of the glomerular filtration barrier PMID: 25273069
    3. The SNP rs17319721 functions as a cis-acting expression quantitative trait locus of SHROOM3 that facilitates TGF-B1 signaling and contributes to allograft injury. PMID: 25437874
    4. RESULTS: rs1260326 in GCKR (beta=1.30, P = 3.23E-03), rs17319721 in SHROOM3 (beta = -1.28, P-value = 3.18E-03) and rs12917707 in UMOD (beta = 2.0, P-value = 8.84E-04) were significantly associated with baseline estimated GFR PMID: 23586973
    5. A recessive missense mutation in SHROOM3 is associated with heterotaxy syndrome. PMID: 21936905

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell junction, adherens junction. Cytoplasm, cytoskeleton. Apical cell membrane; Peripheral membrane protein.
  • 蛋白家族：
    Shroom family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30422

    OMIM: 604570

    KEGG: hsa:57619

    STRING: 9606.ENSP00000296043

    UniGene: Hs.683808