SLC27A1 Antibody
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中文名稱:SLC27A1兔多克隆抗體
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貨號(hào):CSB-PA740768LA01HU
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規(guī)格:¥440
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圖片:
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Immunofluorescence staining of A549 cells with CSB-PA740768LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) SLC27A1 Polyclonal antibody
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Uniprot No.:
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基因名:
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別名:SLC27A1 antibody; ACSVL5 antibody; FATP1Long-chain fatty acid transport protein 1 antibody; FATP-1 antibody; Fatty acid transport protein 1 antibody; EC 6.2.1.- antibody; Solute carrier family 27 member 1 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human Long-chain fatty acid transport protein 1 protein (453-570AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
本頁(yè)面中的產(chǎn)品,SLC27A1 Antibody (CSB-PA740768LA01HU),的標(biāo)記方式是Non-conjugated。對(duì)于SLC27A1 Antibody,我們還提供其他標(biāo)記。見(jiàn)下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, IF
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推薦稀釋比:
Application Recommended Dilution IF 1:50-1:200 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Probably involved in fatty acid transport across the blood barrier.
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基因功能參考文獻(xiàn):
- Neonatal phthalate ester exposure induced placental MTs, FATP1 and HFABP mRNA expression PMID: 26867681
- Several proteins that are expressed in the epidermis have been proposed to facilitate the uptake of long-chain fatty acids (LCFA) in mammalian cells, CD36, fatty acid binding protein, and FATP. [review] PMID: 24120574
- Observational study of gene-disease association. (HuGE Navigator) PMID: 20965718
- Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
- Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
- FATP1 inhibits 11-cis retinol formation via interaction with the visual cycle retinoid isomerase RPE65 and lecithin:retinol acyltransferase PMID: 20356843
- Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20416077
- exogenously supplied fatty acids are preferentially channeled by an FATP1-linked mechanism into the TG biosynthetic pathway; such internalized lipids downregulate de novo sphingomyelin and cholesterol metabolism in growing 293 cells PMID: 12235169
- FATP1 might play a role in post-prandial lipid metabolism and development of cardiovascular disease. PMID: 12818409
- FATP1 stimulated transport and consumption of palmitate and oleate, which they channeled away from complete oxidation and toward TAG synthesis. PMID: 15897321
- These data reveals the localization and points to a regulatory function of FATP1 in myotube mitochondria. PMID: 19361580
- Observational study of gene-disease association. (HuGE Navigator) PMID: 18660489
- Observational study of gene-disease association. (HuGE Navigator) PMID: 12818409
- Observational study of gene-disease association. (HuGE Navigator) PMID: 15978856
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亞細(xì)胞定位:Cell membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Cytoplasm.
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蛋白家族:ATP-dependent AMP-binding enzyme family
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組織特異性:Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver. Expressed in brain gray matter.
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數(shù)據(jù)庫(kù)鏈接:
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