SLC39A5 Antibody
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中文名稱:SLC39A5兔多克隆抗體
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貨號(hào):CSB-PA900358
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規(guī)格:¥1100
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圖片:
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:SLC39A5
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別名:SLC39A5; ZIP5; Zinc transporter ZIP5; Solute carrier family 39 member 5; Zrt- and Irt-like protein 5; ZIP-5
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Synthetic peptide of Human SLC39A5
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
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抗體亞型:IgG
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純化方式:Antigen affinity purification
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA,WB
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推薦稀釋比:
Application Recommended Dilution ELISA 1:1000-1:2000 WB 1:200-1:1000 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera. Plays a role in eye development.
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基因功能參考文獻(xiàn):
- we found that downregulation of ZIP5 by RNA interference inhibited esophageal cancer growth in vivo, reduced the expression of COX2, and promoted the expression of E-cadherin. PMID: 27458102
- ZIP5 knockdown inhibited the proliferation, migration and invasion of ESCC and suppressed COX2, cyclin D1 and E-cadherin expression, which led to the inhibition of cell progression in esophageal squamous cell carcinoma . PMID: 26133979
- mutation in LRPAP1 is associated with high myopia. Further studies are expected to evaluate the pathogenicity of the variants in CTSH, LEPREL1, ZNF644, SLC39A5, and SCO2. PMID: 25525168
- Zip5 protein is a zinc transporter that localizes to the basolateral surface of polarized cells PMID: 15322118
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相關(guān)疾病:Myopia 24, autosomal dominant (MYP24)
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亞細(xì)胞定位:Basolateral cell membrane; Multi-pass membrane protein.
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蛋白家族:ZIP transporter (TC 2.A.5) family
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組織特異性:Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.
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數(shù)據(jù)庫(kù)鏈接:
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