SLC6A17 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q9H1V8
基因名：

SLC6A17
別名：

SLC6A17 antibody; NTT4 antibody; Sodium-dependent neutral amino acid transporter SLC6A17 antibody; Sodium-dependent neurotransmitter transporter NTT4 antibody; Solute carrier family 6 member 17 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the Internal region of Human NTT4.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:5000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent.
基因功能參考文獻：
1. Our genetic findings implicate homozygous SLC6A17 mutations in autosomal-recessive intellectual disability. PMID: 25704603
2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
3. The substrate profile of the NTT4/XT1-dependent activity is similar to that of the closely related B(0)AT2/SBAT1 (SLC6A15), including a submillimolar apparent affinity for proline and leucine and a low millimolar apparent affinity for glutamine. PMID: 19147495
相關疾?。?/div>
Mental retardation, autosomal recessive 48 (MRT48)
亞細胞定位：

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, postsynapse. Cell junction, synapse, presynapse.
蛋白家族：

Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A17 subfamily
數(shù)據(jù)庫鏈接：

HGNC: 31399

OMIM: 610299

KEGG: hsa:388662

STRING: 9606.ENSP00000330199

UniGene: Hs.128382