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SLC7A3 Antibody, FITC conjugated

  • 中文名稱：
    SLC7A3兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA855505LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SLC7A3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SLC7A3
  • 別名：
    SLC7A3 antibody; ATRC3 antibody; CAT3 antibody; Cationic amino acid transporter 3 antibody; CAT-3 antibody; CAT3 antibody; Cationic amino acid transporter y+ antibody; Solute carrier family 7 member 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Cationic amino acid transporter 3 protein (428-475AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner.
  • 基因功能參考文獻：
    1. rare hypomorphic variants of SLC7A3 exist in male individuals, SLC7A3 variants possibly contribute to the etiology of autism spectrum disorders in male subjects in association with other genetic factors PMID: 26215737
    2. knockdown impaired AMPK-PPAR-alpha signaling and resulted in lipid accumulation under glucose starvation in liver cells PMID: 25130427
    3. CAT1, CAT2, and CAT3 localized in adult brains but with uneven distribution. PMID: 22870827
    4. is concluded that hCAT-3 is a passive transport system that conducts monovalent cations including L-Arg. PMID: 15737334
    5. It is concluded that similar to hCAT-1, hCAT-3 activity is decreased by PKC via reduction of transporter molecules in the plasma membrane. PMID: 16332251

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  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Amino acid-polyamine-organocation (APC) superfamily, Cationic amino acid transporter (CAT) (TC 2.A.3.3) family
  • 組織特異性：
    Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11061

    OMIM: 300443

    KEGG: hsa:84889

    STRING: 9606.ENSP00000298085

    UniGene: Hs.175220