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  4. SLCO3A1 Antibody, Biotin conjugated

SLCO3A1 Antibody, Biotin conjugated

  • 中文名稱：
    SLCO3A1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA883432LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SLCO3A1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SLCO3A1
  • 別名：
    SLCO3A1 antibody; OATP3A1 antibody; OATPD antibody; SLC21A11 antibody; Solute carrier organic anion transporter family member 3A1 antibody; OATP3A1 antibody; Organic anion transporter polypeptide-related protein 3 antibody; OATP-RP3 antibody; OATPRP3 antibody; Organic anion-transporting polypeptide D antibody; OATP-D antibody; PGE1 transporter antibody; Sodium-independent organic anion transporter D antibody; Solute carrier family 21 member 11 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Solute carrier organic anion transporter family member 3A1 protein (439-539AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3-sulfate, taurocholate, digoxin nor DHEAS.
  • 基因功能參考文獻(xiàn)：
    1. OATP3A1 functions as a bile acid efflux transporter that is up-regulated as an adaptive response to cholestasis. PMID: 30063921
    2. SLCO3A1, a novel Crohn's disease-associated gene, mediates inflammatory processes in intestinal epithelial cells through NF-kappaB transcription activation. PMID: 24945726
    3. Single nucleotide polymorhpisms of SLCO3A1 were associated with nicotine dependence. PMID: 22377092
    4. OATP-D plays an important role in translocating prostaglandins in specialized tissues and cells. PMID: 14631946
    5. Further evidence is provided for the involvement of OATPs in oligopeptide transport. OATP3A1 variants might be involved in the regulation of extracellular vasopressin concentration in human brain. PMID: 16971491

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  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Organo anion transporter (TC 2.A.60) family
  • 組織特異性：
    Ubiquitous. Highly expressed in spleen and leukocytes. Generally the expression of isoform 1 is higher than that of isoform 2. Isoform 2 is particularly abundant in testis and brain. In testis, isoform 1 is detected in spermatogonia at different stages an
  • 數(shù)據(jù)庫鏈接：

    HGNC: 10952

    OMIM: 612435

    KEGG: hsa:28232

    STRING: 9606.ENSP00000320634

    UniGene: Hs.311187