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  4. ST3GAL3 Antibody, FITC conjugated

ST3GAL3 Antibody, FITC conjugated

  • 中文名稱：
    ST3GAL3兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA606136LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ST3GAL3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ST3GAL3
  • 別名：
    3 sialyltransferase antibody; 3(4) GlcNAc alpha-2 antibody; 3-sialyltransferase 3 antibody; 3-sialyltransferase antibody; 3-ST 3 antibody; 4-galactoside alpha-2 antibody; 4GlcNAc alpha 2 3 sialyltransferase antibody; Alpha 2 3 sialyltransferase II antibody; Alpha 2 3 sialyltransferase III antibody; Alpha 2 3 ST 3 antibody; Alpha 2 antibody; Beta galactoside alpha 3 sialyltransferase 3 antibody; Beta-galactoside alpha-2 antibody; CMP N acetylneuraminate beta 1 4 galactoside alpha 2 3 sialyltransferase antibody; CMP-N-acetylneuraminate-beta-1 antibody; EC 2.4.99.6 antibody; Gal beta 1 3 antibody; Gal beta 1 3(4) GlcNAc alpha 2 3 sialyltransferase antibody; Gal beta 1 3(4)GlcNAc alpha 2 3 sialyltransferase antibody; Gal beta-1 antibody; N acetyllactosaminide alpha 2 3 sialyltransferase antibody; N-acetyllactosaminide alpha-2 antibody; OTTHUMP00000008820 antibody; OTTHUMP00000008821 antibody; OTTHUMP00000008822 antibody; OTTHUMP00000008823 antibody; Sialyltransferase 6 (N acetyllacosaminide alpha 2 3 sialyltransferase) antibody; Sialyltransferase 6 antibody; SIAT6 antibody; SIAT6_HUMAN antibody; ST3 beta galactoside alpha 2 3 sialyltransferase 3 antibody; ST3 beta galactoside alpha 2,3 sialyltransferase 3 antibody; ST3Gal III antibody; St3gal3 antibody; ST3GALII antibody; ST3GalIII antibody; ST3N antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase protein (29-375AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc.
  • 基因功能參考文獻(xiàn)：
    1. CA19.9 appears as a physiological product whose synthesis strongly depends on the tissue specific and epigenetically-regulated expression of B3GALT5 and ST3GAL3. PMID: 27535614
    2. ST3Gal3 knockdown synergistically enhanced cisplatin-induced apoptosis in ovarian cancer cells PMID: 27871859
    3. ST3Gal III modulates breast cancer cell adhesion and invasion by altering the expression of invasion-related molecules. PMID: 27779707
    4. Dysfunctional ST3GAL3 may result in perturbation of the posttranslational sialylation of proteins in these pathways PMID: 23252400
    5. ST3GAL3 mutations impair the development of higher cognitive functions. PMID: 21907012
    6. Characterization of the promoter region of the ST3Gal III gene. PMID: 12697334
    7. 19 different transcripts of ST3GalIII were isolated and cloned; tissue distribution analysis showed complex patterns in neural and muscular tissues PMID: 12815231
    8. High levels of ST3GAL-III in the tumor tissue correlated with secondary local tumor recurrence (p = 0.005; p = 0.012). PMID: 12931020
    9. Identification of a new ST3Gal3 transcript from fetal brain. PMID: 15316282

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  • 相關(guān)疾?。?/div>
    Mental retardation, autosomal recessive 12 (MRT12); Epileptic encephalopathy, early infantile, 15 (EIEE15)
  • 亞細(xì)胞定位：
    Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
  • 蛋白家族：
    Glycosyltransferase 29 family
  • 組織特異性：
    Highly expressed in adult skeletal muscle and in all fetal tissues examined and to a much lesser extent in placenta, lung and liver.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 10866

    OMIM: 606494

    KEGG: hsa:6487

    UniGene: Hs.597915