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  4. ST3GAL6 Antibody

ST3GAL6 Antibody

  • 中文名稱：
    ST3GAL6兔多克隆抗體
  • 貨號：
    CSB-PA022756GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    ST3GAL6
  • 別名：
    ibody; 3-sialyltransferase VI antibody; alpha-2,3-sialyltransferase VI antibody; alpha2,3-sialyltransferase antibody; CMP-NeuAc:beta-galactoside alpha-2 antibody; CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI antibody; SIA10_HUMAN antibody; Sialyltransferase 10 antibody; ST3Gal VI antibody; ST3GAL6 antibody; ST3GalVI antibody; Type 2 lactosamine alpha-2,3-sialyltransferase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human ST3GAL6
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1.
  • 基因功能參考文獻：
    1. The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma. PMID: 25061176
    2. the occurrence of CD75s- and iso-CD75s-gangliosides in tumor tissues is largely independent of the transcriptional expression of ST6GAL1 and ST3GAL6 PMID: 21147760
    3. Expression of ST3Gal IV in several gastrointestinal cell lines is correlated with the expression of sialyl Lewis x at the cell surface. PMID: 19781661
    4. Epigenetic changes in a group of glycosyltransferases including B4GALNT2 and ST3GAL6 represent a malignant phenotype of gastric cancer caused by silencing of the activity of these enzymes PMID: 18485915
  • 亞細(xì)胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 29 family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18080

    OMIM: 607156

    KEGG: hsa:10402

    STRING: 9606.ENSP00000377717

    UniGene: Hs.148716