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STK17A Antibody

  • 中文名稱：
    STK17A兔多克隆抗體
  • 貨號(hào)：
    CSB-PA022837GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    STK17A
  • 別名：
    DAP kinase-related apoptosis-inducing protein kinase 1 antibody; death-associated protein kinase-related 1 antibody; DRAK1 antibody; EC 2.7.11.1 antibody; Serine / threonine kinase 17a death associated protein kinase related 1 antibody; Serine/threonine kinase 17a antibody; Serine/threonine protein kinase 17a antibody; Serine/threonine-protein kinase 17A antibody; ST17A_HUMAN antibody; STK17 A antibody; STK17A antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Human STK17A
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species.
  • 基因功能參考文獻(xiàn)：
    1. These findings suggest that DRAK1 translocates in response to stimuli and induces apoptosis through its interaction with specific binding partners, p53 and/or ANT2. PMID: 29397938
    2. the present study was the first to find localization of STK17A in normal bile canaliculi. PMID: 26305096
    3. DRAK1 was predominantly localized in the cytoplasm and bound to Smad3, thereby interrupting Smad3/Smad4 complex formation, which is the core process for the induction of tumor suppressor genes by TGF-beta1 PMID: 25531329
    4. STK17A provides a proliferative and survival advantage to GBM cells PMID: 24312360
    5. When analyzing STK17A haplotypes distribution, we found association between TGGTC, TAGTC and AAGAT haplotypes and risk to develop SLE PMID: 23860322
    6. identified STK17A as a novel direct target of p53 and a modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells. PMID: 21489989

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  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily
  • 組織特異性：
    Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 11395

    OMIM: 604726

    KEGG: hsa:9263

    STRING: 9606.ENSP00000319192

    UniGene: Hs.709489