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SVBP Antibody

  • 中文名稱：
    SVBP兔多克隆抗體
  • 貨號(hào)：
    CSB-PA836653LA01HU
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SVBP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SVBP
  • 別名：
    SVBP antibody; CCDC23 antibody; Small vasohibin-binding protein antibody; Coiled coil domain-containing protein 23 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Small vasohibin-binding protein (1-66AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，SVBP Antibody (CSB-PA836653LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于SVBP Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA836653LB01HU SVBP Antibody, HRP conjugated ELISA
    FITC CSB-PA836653LC01HU SVBP Antibody, FITC conjugated
    Biotin CSB-PA836653LD01HU SVBP Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin. This activity is critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning. Also required to enhance the solubility and secretion of VASH1 and VASH2. Plays a role in axon and excitatory synapse formation.
  • 基因功能參考文獻(xiàn)：
    1. identified a novel UPS regulatory system in which essential domain architecture (VASH-PS) of VASHs, comprising regions VASH191-180 and VASH280-169 , regulate the cytosolic punctate structure formation in the absence of SVBP. PMID: 27879017
    2. VASH2 contributes to the angiogenesis in hepatocellular carcinoma via an SVBP-mediated paracrine mechanism. PMID: 22614011
    3. SVBP(CCDC23)acts as a secretory chaperone for VASH1. PMID: 20736312
  • 亞細(xì)胞定位：
    Cytoplasm. Secreted. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    SVBP family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 29204

    OMIM: 617853

    KEGG: hsa:374969

    STRING: 9606.ENSP00000361599

    UniGene: Hs.113919