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  4. TDRD9 Antibody, FITC conjugated

TDRD9 Antibody, FITC conjugated

  • 中文名稱：
    TDRD9兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA850866LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TDRD9 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TDRD9
  • 別名：
    C14orf75 antibody; chromosome 14 open reading frame 75 antibody; DKFZp434N0820 antibody; FLJ36164 antibody; HIG 1 antibody; Hypoxia inducible HIG 1 antibody; MGC135025 antibody; NET54 antibody; Putative ATP dependent RNA helicase TDRD9 antibody; Putative ATP-dependent RNA helicase TDRD9 antibody; TDRD 9 antibody; Tdrd9 antibody; TDRD9_HUMAN antibody; Tudor domain containing 9 antibody; Tudor domain containing protein 9 antibody; Tudor domain-containing protein 9 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Putative ATP-dependent RNA helicase TDRD9 protein (286-585AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    ATP-binding RNA helicase required during spermatogenesis. Required to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Acts downstream of piRNA biogenesis: exclusively required for transposon silencing in the nucleus, suggesting that it acts as a nuclear effector in the nucleus together with PIWIL4.
  • 基因功能參考文獻：
    1. first report of a recessive deleterious mutation in TDRD9 in humans; study demonstrates that non-obstructive azoospermia can be caused by a mutation in TDRD9 PMID: 28536242
  • 相關(guān)疾?。?/div>
    Defects in TDRD9 may be a cause of non-obstructive azoospermia, a disorder characterized by the absence of sperm. Female fertility is not affected.
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    DEAD box helicase family, DEAH subfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20122

    KEGG: hsa:122402

    STRING: 9606.ENSP00000387303

    UniGene: Hs.21454