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  4. TFC3 Antibody

TFC3 Antibody

Rare Species
  • 中文名稱：
    TFC3兔多克隆抗體
  • 貨號：
    CSB-PA339415XA01SVG
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: TFC3 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 56.1 kDa
      Observed band size: 63 kDa
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TFC3
  • 別名：
    Transcription factor tau 138 kDa subunit (TFIIIC 138 kDa subunit) (Transcription factor C subunit 3) TFC3 TSV115 YAL001C FUN24
  • 反應種屬：
    Escherichia coli(strain K12)
  • 免疫原：
    Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) TFC3 protein
  • 免疫原種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Protein G
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function. Part of the tauB domain of TFIIIC that binds boxB DNA promoter sites of tRNA and similar genes. TFC3 is essential for cell viability. Cooperates with TFC6 in DNA binding.
  • 基因功能參考文獻：
    1. tau55-HPD and Huf as bona fide protein phosphatases, characterize their substrate specificities, and provide a small set of regulated phosphosite targets in vivo. PMID: 23569204
    2. the TFC6 promoter is directly regulated by the TF(III)C complex, a demonstration of an RNA polymerase II promoter being directly responsive to a core Pol III transcription factor complex. PMID: 21536876
    3. Partially assembled Pol III complexes containing only the TFIIIC exhibit chromatin boundary functions both as heterochromatin barriers and as insulators to gene activation. PMID: 18849469
  • 亞細胞定位：
    Nucleus. Mitochondrion.
  • 數(shù)據(jù)庫鏈接：

    KEGG: sce:YAL001C

    STRING: 4932.YAL001C