TGDS Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

O95455
基因名：

TGDS
別名：

6-dehydratase antibody; dTDP D glucose 4,6 dehydratase antibody; dTDP-D-glucose 4 antibody; Growth inhibiting protein 21 antibody; SDR2E1 antibody; TDP glucose 4,6 dehydratase antibody; TDPGD antibody; TGDS antibody; TGDS_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human TGDS
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

基因功能參考文獻：
1. Our findings widen the phenotype spectrum caused by TGDS mutations and underline the phenotypic overlap with Temtamy preaxial brachydactyly syndrome. This improves our understanding of the prenatal development and the pathogenetic mechanism of Catel-Manzke syndrome. PMID: 28422407
2. By using haplotype reconstruction we showed that the mutation c.298G>T is probably a founder mutation. Due to the spectrum of the amino acid changes, we suggest that loss of function in TGDS is the underlying mechanism of Catel-Manzke syndrome. PMID: 25480037
相關疾病：

Catel-Manzke syndrome (CATMANS)
蛋白家族：

NAD(P)-dependent epimerase/dehydratase family, dTDP-glucose dehydratase subfamily
數(shù)據(jù)庫鏈接：

HGNC: 20324

OMIM: 616145

KEGG: hsa:23483

STRING: 9606.ENSP00000261296

UniGene: Hs.12393