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TIMM17A Antibody

  • 中文名稱：
    TIMM17A兔多克隆抗體
  • 貨號：
    CSB-PA860770ESR1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA860770ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA860770ESR1HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TIMM17A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TIMM17A
  • 別名：
    Inner membrane preprotein translocase Tim17a antibody; Mitochondrial import inner membrane translocase subunit Tim17-A antibody; mitochondrial inner membrane translocase antibody; preprotein translocase antibody; TI17A_HUMAN antibody; TIM17 antibody; TIM17A antibody; TIMM17A antibody; translocase of inner mitochondrial membrane 17 homolog A (yeast) antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Mitochondrial import inner membrane translocase subunit Tim17-A protein (1-171AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
  • 基因功能參考文獻(xiàn)：
    1. TIMM17A has a profound impact on the cellular function of breast cancer cells. A decrease of TIMM17A expression is associated with the reduction of the aggressiveness of breast cancer cells. PMID: 26977020
    2. High TIMM17A expression is associated with adverse pathological outcomes in breast cancer. PMID: 20972741
    3. mRNA expression analysis and immunohistochemistry analysis in breast cancer tissues indicated that expression level of TIMM17A was directly correlated with tumor progression; survival analysis suggested TIMM17A was a prognosis factor in breast cancer. PMID: 20198662
    4. Tim17 is a conserved suppressor of mtDNA instability. PMID: 18826960
  • 亞細(xì)胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Tim17/Tim22/Tim23 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17315

    OMIM: 605057

    KEGG: hsa:10440

    STRING: 9606.ENSP00000356256

    UniGene: Hs.20716