TIMM44 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

O43615
基因名：

TIMM44
別名：

TIMM44 antibody; MIMT44 antibody; TIM44 antibody; Mitochondrial import inner membrane translocase subunit TIM44 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human TIMM44
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source.
基因功能參考文獻：
1. TIM44 was identified for the first time as a potential oncogene, which plays an important role in autophagy through the TIM44-SOD2-ROS-mTOR pathway. PMID: 27849558
2. The Timm44 gene may be a new target for the treatment of type 2 diabetes PMID: 25749183
3. This protein has been found differentially expressed in thalami from patients with schizophrenia. PMID: 20471030
亞細胞定位：

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Mitochondrion matrix.
蛋白家族：

Tim44 family
數(shù)據(jù)庫鏈接：

HGNC: 17316

OMIM: 605058

KEGG: hsa:10469

STRING: 9606.ENSP00000270538

UniGene: Hs.465784