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TMEM98 Antibody

  • 中文名稱：
    TMEM98兔多克隆抗體
  • 貨號：
    CSB-PA023901LA01HU
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TMEM98 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TMEM98
  • 別名：
    TMEM98 antibody; UNQ536/PRO1079 antibody; Transmembrane protein 98 antibody; Protein TADA1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Transmembrane protein 98 protein (25-226AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，TMEM98 Antibody (CSB-PA023901LA01HU)，的標(biāo)記方式是Non-conjugated。對于TMEM98 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA023901LB01HU TMEM98 Antibody, HRP conjugated ELISA
    FITC CSB-PA023901LC01HU TMEM98 Antibody, FITC conjugated
    Biotin CSB-PA023901LD01HU TMEM98 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation. The secreted form promotes differentiation of T helper 1 cells (Th1).
  • 基因功能參考文獻(xiàn)：
    1. siRNA-TMEM98 inhibited the invasion and migration of non-small cell lung cancer cells. PMID: 26884835
    2. Two novel TMEM98 mutations have been found in two pedigrees with autosomal dominant nanophthalmos. PMID: 26392740
    3. we identified a panel of novel common chemoresistance-associated genes and demonstrated that TMEM98 is a chemoresistance-conferring gene in hepatocellular carcinoma. PMID: 24608572
    4. A novel gene associated with nanophthalmos, TMEM98 most likely represents the cause of the disease. PMID: 24852644
  • 相關(guān)疾病：
    Nanophthalmos 4 (NNO4)
  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type II membrane protein. Secreted. Secreted, extracellular exosome. Endoplasmic reticulum membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    TMEM98 family
  • 組織特異性：
    Widely expressed with high expression in the ovary, pancreas and prostate. Expressed in the eye, particularly in corneal endothelium, iris, ciliary body, sclera, optic nerve, optic nerve head, and retina. Expressed by activated peripheral blood mononuclea
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24529

    OMIM: 615949

    KEGG: hsa:26022

    STRING: 9606.ENSP00000378138

    UniGene: Hs.3447