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TNFAIP2 Antibody

  • 中文名稱：
    TNFAIP2兔多克隆抗體
  • 貨號：
    CSB-PA023957LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Mouse liver tissue
      All lanes: TNFAIP2 antibody at 6.9μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 73 kDa
      Observed band size: 73 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TNFAIP2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TNFAIP2
  • 別名：
    B94 antibody; EXOC3L3 antibody; exocyst complex component 3-like 3 antibody; Primary response gene B94 protein antibody; TNAP2_HUMAN antibody; TNF alpha-induced protein 2 antibody; Tnfaip2 antibody; tumor necrosis factor alpha induced protein 2 antibody; Tumor necrosis factor alpha-induced protein 2 antibody; tumor necrosis factor, alpha-induced protein 2 antibody antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Tumor necrosis factor alpha-induced protein 2 protein (1-93AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，TNFAIP2 Antibody (CSB-PA023957LA01HU)，的標(biāo)記方式是Non-conjugated。對于TNFAIP2 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA023957LB01HU TNFAIP2 Antibody, HRP conjugated ELISA
    FITC CSB-PA023957LC01HU TNFAIP2 Antibody, FITC conjugated
    Biotin CSB-PA023957LD01HU TNFAIP2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May play a role as a mediator of inflammation and angiogenesis.
  • 基因功能參考文獻(xiàn)：
    1. A polarized secretion assay suggested that the silencing of endothelial myeloid-secretory impairs T effector transendothelial migration by reducing the preferential secretion of endothelial-produced CCL2. PMID: 26701136
    2. Data indicate that TNFAIP2 overexpression may facilitate proliferation and metastasis via activation of the Wnt/beta-catenin signaling pathway in esophageal squamous cell carcinoma. PMID: 28393234
    3. Taken together, genome-wide chromatin analysis of Legionella pneumophila-infected macrophages demonstrated induction of TNFAIP2, a NF-kappaB-dependent factor relevant for bacterial replication. PMID: 27130431
    4. data suggest that TNFAIP2 is a novel inhibitor of NF-kappa-B that acts as an autoinhibitor of the TNFalpha response during septic shock. PMID: 26347487
    5. findings collectively suggest that TNFAIP2 is a direct KLF5 target gene, and both KLF5 and TNFAIP2 promote breast cancer cell proliferation, migration and invasion through Rac1 and Cdc42 PMID: 26189798
    6. A functional TNFAIP2 3'-UTR rs8126 genetic polymorphism contributes to risk of esophageal squamous cell carcinoma. PMID: 25383966
    7. the regulation of TNFAIP2 and its role in promoting NPC tumor progression PMID: 23975427
    8. The TNFAIP2 miRNA binding site rs8126 T>C single nucleotide polymorphism may be a marker for susceptibility to gastric cancer. PMID: 23724109
    9. A functional variant at the miR-184 binding site in TNFAIP2 is associated with squamous cell carcinoma of the head and neck. PMID: 21934093
    10. TNFAIP2 may serve as a useful new marker of dendritic and histiocytic sarcomas. PMID: 21921781
    11. TNFAIP2 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
    12. TNFAIP2 is a cell migration-promoting protein and its expression predicts distant metastasis. Our data suggest that TNFAIP2 may serve as an independent prognostic indicator for nasopharyngeal carcinoma. PMID: 21057457

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  • 蛋白家族：
    SEC6 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11895

    OMIM: 603300

    KEGG: hsa:7127

    STRING: 9606.ENSP00000332326

    UniGene: Hs.525607