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TNFSF12 Antibody

  • 中文名稱：
    TNFSF12兔多克隆抗體
  • 貨號(hào)：
    CSB-PA023987ESR1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA023987ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human epityphlon tissue using CSB-PA023987ESR1HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TNFSF12 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    APO 3 ligand antibody; APO 3L antibody; APO3 ligand antibody; APO3/DR3 ligand antibody; APO3L antibody; DR3LG antibody; MGC129581 antibody; MGC20669 antibody; secreted form antibody; TNF-related weak inducer of apoptosis antibody; TNF12_HUMAN antibody; TNFSF 12 antibody; Tnfsf12 antibody; TNFSF12 protein antibody; Tumor necrosis factor (ligand) superfamily member 12 antibody; Tumor necrosis factor ligand superfamily member 12 antibody; Tumor necrosis factor superfamily member 12 antibody; TWEAK antibody; UNQ181/PRO207 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Tumor necrosis factor ligand superfamily member 12 protein (42-123AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
  • 基因功能參考文獻(xiàn)：
    1. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
    2. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type II membrane protein.; [Tumor necrosis factor ligand superfamily member 12, secreted form]: Secreted.; [Isoform TWE-PRIL]: Cell membrane; Single-pass membrane protein.
  • 蛋白家族：
    Tumor necrosis factor family
  • 組織特異性：
    Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Als
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 11927

    OMIM: 602695

    KEGG: hsa:407977

    UniGene: Hs.54673