TOE1 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q96GM8
基因名：

TOE1
別名：

Target of EGR1 protein 1 antibody; target of EGR1; member 1 antibody; Toe1 antibody; TOE1_HUMAN antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human TOE1
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IHC,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing.
基因功能參考文獻(xiàn)：
1. Human cells with reduced levels of TOE1 accumulated 3'-end-extended pre-snRNA. PMID: 28092684
2. Antiviral potency of TOE1 and its cell-penetrating capability have been identified to lie within a 35-amino-acid region containing the nuclear localization sequence PMID: 26056259
3. TOE1 has a role in the growth inhibitory activity of Egr1 PMID: 12562764
相關(guān)疾病：

Pontocerebellar hypoplasia 7 (PCH7)
亞細(xì)胞定位：

Nucleus, nucleolus. Nucleus speckle. Note=Localizes to nuclear speckles.
蛋白家族：

CAF1 family
組織特異性：

Widely expressed.
數(shù)據(jù)庫鏈接：

HGNC: 15954

OMIM: 613931

KEGG: hsa:114034

STRING: 9606.ENSP00000361162

UniGene: Hs.525091