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TRIM26 Antibody, FITC conjugated

  • 中文名稱：
    TRIM26兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA619638LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TRIM26 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TRIM26
  • 別名：
    Acid finger protein antibody; AFP antibody; CAM25547 antibody; RING finger protein 95 antibody; RNF95 antibody; TRI26_HUMAN antibody; TRIM26 antibody; tripartite motif containing 26 antibody; Tripartite motif-containing protein 26 antibody; widely expressed acid zinc finger protein antibody; Zinc finger protein 173 antibody; Zinc finger protein 173; formerly antibody; ZNF173 antibody; ZNF173; formerly antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Tripartite motif-containing protein 26 protein (151-270AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.
  • 基因功能參考文獻(xiàn)：
    1. Autoubiquitination of TRIM26 links TBK1 to NEMO in RLR-mediated innate antiviral immune response PMID: 26611359
    2. Down-regulation of TRIM26 is associated with worse prognosis of hepatocellular carcinoma. PMID: 26043685
    3. In addition to confirming one of the top findings in the meta-analysis, TRIM26, RNF5 and HLA-DRB3 have been identified as potential candidate genes for schizophrenia. PMID: 22433715
    4. The study reports no associations between polymorphisms in TRIM26 and the risk of aspirin-exacerbated respiratory disease in both logistic and regression analyses. PMID: 22294275
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    TRIM/RBCC family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 12962

    OMIM: 600830

    KEGG: hsa:7726

    STRING: 9606.ENSP00000391879

    UniGene: Hs.485041