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TRIT1 Antibody

  • 中文名稱：
    TRIT1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA867142LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: TRIT1 antibody at 3µg/ml
      Lane 1: Jurkat whole cell lysate
      Lane 2: Raji whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 53, 38, 50, 44, 19 kDa
      Observed band size: 53 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA867142LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TRIT1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TRIT1
  • 別名：
    2310075G14Rik antibody; AI314189 antibody; AI314635 antibody; AV099619 antibody; FLJ20061 antibody; hGRO1 antibody; IPP transferase antibody; IPPT antibody; IPT antibody; IPTase antibody; Isopentenyl diphosphate:tRNA isopentenyltransferase antibody; Isopentenyl-diphosphate:tRNA isopentenyltransferase antibody; MGC149242 antibody; MGC149243 antibody; mitochondrial antibody; MOD5 antibody; MOD5_HUMAN antibody; OTTMUSP00000009314 antibody; Putative protein TR2IT1 antibody; RP23-121J14.6 antibody; TRIT 1 antibody; TRIT1 antibody; tRNA dimethylallyltransferase antibody; tRNA isopentenylpyrophosphate transferase antibody; tRNA isopentenyltransferase 1 antibody; tRNA isopentenyltransferase antibody; tRNA isopentenyltransferase mitochondrial antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human tRNA dimethylallyltransferase protein (1-324AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，TRIT1 Antibody (CSB-PA867142LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于TRIT1 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA867142LB01HU TRIT1 Antibody, HRP conjugated ELISA
    FITC CSB-PA867142LC01HU TRIT1 Antibody, FITC conjugated
    Biotin CSB-PA867142LD01HU TRIT1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
  • 基因功能參考文獻(xiàn)：
    1. We show that dysfunctional TRIT1 results in decreased levels of select mitochondrial proteins. Our findings confirm the TRIT1 disease association and advance the phenotypic and molecular understanding of this disorder. PMID: 28185376
    2. characterize TRIT1 as a novel human amyloid fiber forming protein. We discuss these data in light of TRIT1's functional roles and possible implications for disease PMID: 27984194
    3. patient cells bearing the p.Arg323Gln TRIT1 mutation are severely deficient in i6A37 in both cytosolic and mitochondrial tRNAs PMID: 24901367
    4. In light of this additional nuclear role for Mod5 we discuss the proposed role of the human homologue of Mod5, TRIT1, as a tumor suppressor protein.[review] PMID: 25261850
    5. TRIT1 may control the levels of some tRNAs as well as their specific activity. PMID: 24126054
    6. One TRIT1 haplotype, CCGT, was associated with lymph node metastasis. PMID: 23349019
    7. The rare allele of TRIT1 Phe202Leu SNP was approximately seven-fold more frequent in Asian than in Caucasian subjects and three additional SNPs in the TRIT1 gene showed ethnic differences in allelic frequencies PMID: 17145094

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  • 亞細(xì)胞定位：
    [Isoform 1]: Mitochondrion.; [Isoform 4]: Mitochondrion.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 5]: Cytoplasm.
  • 蛋白家族：
    IPP transferase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20286

    OMIM: 617840

    KEGG: hsa:54802

    STRING: 9606.ENSP00000321810

    UniGene: Hs.356554