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TRMT112 Antibody

  • 中文名稱:
    TRMT112兔多克隆抗體
  • 貨號:
    CSB-PA883416LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA883416LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA883416LA01HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) TRMT112 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TRMT112
  • 別名:
    TRMT112 antibody; AD-001 antibody; HSPC152 antibody; HSPC170 antibody; Multifunctional methyltransferase subunit TRM112-like protein antibody; tRNA methyltransferase 112 homolog antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human tRNA methyltransferase 112 homolog protein (1-125AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated

    本頁面中的產(chǎn)品,TRMT112 Antibody (CSB-PA883416LA01HU),的標(biāo)記方式是Non-conjugated。對于TRMT112 Antibody,我們還提供其他標(biāo)記。見下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA883416LB01HU TRMT112 Antibody, HRP conjugated ELISA
    FITC CSB-PA883416LC01HU TRMT112 Antibody, FITC conjugated
    Biotin CSB-PA883416LD01HU TRMT112 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with HEMK2/N6AMT1 also monomethylates 'Lys-12' of histone H4 (H4K12me1). The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production. Together with methyltransferase METTL5, specifically methylates the 6th position of adenine in position 1832 of 18S rRNA.
  • 基因功能參考文獻(xiàn):
    1. The localization of the TRMT112 protein is determined by WBSCR22, and the WBSCR22-TRMT112 complex is localized in the cell nucleus. PMID: 26214185
  • 亞細(xì)胞定位:
    Nucleus, nucleoplasm. Cytoplasm, perinuclear region.
  • 蛋白家族:
    TRM112 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 26940

    KEGG: hsa:51504

    STRING: 9606.ENSP00000438349

    UniGene: Hs.333579